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FGFR3 promotes the growth and malignancy of melanoma by influencing EMT and the phosphorylation of ERK, AKT, and EGFR

BACKGROUND: Overexpression of fibroblast growth factor receptor 3 (FGFR3) has been linked to tumor progression in many types of cancer. The role of FGFR3 in melanoma remains unclear. In this study, we aimed to uncover the role of FGFR3 in the growth and metastasis of melanoma. METHODS: FGFR3 knockdo...

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Detalles Bibliográficos
Autores principales: Li, Lei, Zhang, Shuai, Li, Hao, Chou, Haiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796326/
https://www.ncbi.nlm.nih.gov/pubmed/31619201
http://dx.doi.org/10.1186/s12885-019-6161-8