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FGFR3 promotes the growth and malignancy of melanoma by influencing EMT and the phosphorylation of ERK, AKT, and EGFR
BACKGROUND: Overexpression of fibroblast growth factor receptor 3 (FGFR3) has been linked to tumor progression in many types of cancer. The role of FGFR3 in melanoma remains unclear. In this study, we aimed to uncover the role of FGFR3 in the growth and metastasis of melanoma. METHODS: FGFR3 knockdo...
Autores principales: | Li, Lei, Zhang, Shuai, Li, Hao, Chou, Haiyan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796326/ https://www.ncbi.nlm.nih.gov/pubmed/31619201 http://dx.doi.org/10.1186/s12885-019-6161-8 |
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