Hemimethylation of CpG dyads is characteristic of secondary DMRs associated with imprinted loci and correlates with 5-hydroxymethylcytosine at paternally methylated sequences

BACKGROUND: In mammals, the regulation of imprinted genes is controlled by differential methylation at imprinting control regions which acquire parent of origin-specific methylation patterns during gametogenesis and retain differences in allelic methylation status throughout fertilization and subseq...

Descripción completa

Detalles Bibliográficos
Autores principales: Nechin, Julianna, Tunstall, Emma, Raymond, Naideline, Hamagami, Nicole, Pathmanabhan, Chris, Forestier, Samantha, Davis, Tamara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796366/
https://www.ncbi.nlm.nih.gov/pubmed/31623686
http://dx.doi.org/10.1186/s13072-019-0309-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796366/
https://www.ncbi.nlm.nih.gov/pubmed/31623686
http://dx.doi.org/10.1186/s13072-019-0309-2

Ejemplares similares