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Hemimethylation of CpG dyads is characteristic of secondary DMRs associated with imprinted loci and correlates with 5-hydroxymethylcytosine at paternally methylated sequences
BACKGROUND: In mammals, the regulation of imprinted genes is controlled by differential methylation at imprinting control regions which acquire parent of origin-specific methylation patterns during gametogenesis and retain differences in allelic methylation status throughout fertilization and subseq...
Autores principales: | Nechin, Julianna, Tunstall, Emma, Raymond, Naideline, Hamagami, Nicole, Pathmanabhan, Chris, Forestier, Samantha, Davis, Tamara L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796366/ https://www.ncbi.nlm.nih.gov/pubmed/31623686 http://dx.doi.org/10.1186/s13072-019-0309-2 |
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