Inhibition of Polycomb Repressive Complex 2 activity reduces trimethylation of H3K27 and affects development in Arabidopsis seedlings

BACKGROUND: Polycomb repressive complex 2 (PRC2) is an epigenetic transcriptional repression system, whose catalytic subunit (ENHANCER OF ZESTE HOMOLOG 2, EZH2 in animals) is responsible for trimethylating histone H3 at lysine 27 (H3K27me3). In mammals, gain-of-function mutations as well as overexpr...

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Detalles Bibliográficos
Autores principales: Ruta, Veronica, Longo, Chiara, Boccaccini, Alessandra, Madia, Valentina Noemi, Saccoliti, Francesco, Tudino, Valeria, Di Santo, Roberto, Lorrai, Riccardo, Dello Ioio, Raffaele, Sabatini, Sabrina, Costi, Roberta, Costantino, Paolo, Vittorioso, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796367/
https://www.ncbi.nlm.nih.gov/pubmed/31619182
http://dx.doi.org/10.1186/s12870-019-2057-7

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