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NANOG helps cancer cells escape NK cell attack by downregulating ICAM1 during tumorigenesis

BACKGROUND: At the beginning of tumorigenesis, newly born cancer cells must successfully avoid attack by the immune system. Although most abnormal cells are efficiently identified and destroyed by the immune system, particularly by NK cells, the molecular mechanisms by which newly born cancer cells...

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Detalles Bibliográficos
Autores principales: Saga, Kotaro, Park, Jinhee, Nimura, Keisuke, Kawamura, Norihiko, Ishibashi, Airi, Nonomura, Norio, Kaneda, Yasufumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796413/
https://www.ncbi.nlm.nih.gov/pubmed/31619256
http://dx.doi.org/10.1186/s13046-019-1429-z