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NANOG helps cancer cells escape NK cell attack by downregulating ICAM1 during tumorigenesis
BACKGROUND: At the beginning of tumorigenesis, newly born cancer cells must successfully avoid attack by the immune system. Although most abnormal cells are efficiently identified and destroyed by the immune system, particularly by NK cells, the molecular mechanisms by which newly born cancer cells...
Autores principales: | Saga, Kotaro, Park, Jinhee, Nimura, Keisuke, Kawamura, Norihiko, Ishibashi, Airi, Nonomura, Norio, Kaneda, Yasufumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796413/ https://www.ncbi.nlm.nih.gov/pubmed/31619256 http://dx.doi.org/10.1186/s13046-019-1429-z |
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