The caudate nucleus undergoes dramatic and unique transcriptional changes in human prodromal Huntington’s disease brain

BACKGROUND: The mechanisms underlying neurodegeneration in the striatum of Huntingon’s Disease (HD) brain are currently unknown. While the striatum is massively degenerated in symptomatic individuals, which makes cellular characterization difficult, it is largely intact in asymptomatic HD gene posit...

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Detalles Bibliográficos
Autores principales: Agus, Filisia, Crespo, Diego, Myers, Richard H., Labadorf, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796419/
https://www.ncbi.nlm.nih.gov/pubmed/31619230
http://dx.doi.org/10.1186/s12920-019-0581-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796419/
https://www.ncbi.nlm.nih.gov/pubmed/31619230
http://dx.doi.org/10.1186/s12920-019-0581-9

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