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The caudate nucleus undergoes dramatic and unique transcriptional changes in human prodromal Huntington’s disease brain
BACKGROUND: The mechanisms underlying neurodegeneration in the striatum of Huntingon’s Disease (HD) brain are currently unknown. While the striatum is massively degenerated in symptomatic individuals, which makes cellular characterization difficult, it is largely intact in asymptomatic HD gene posit...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796419/ https://www.ncbi.nlm.nih.gov/pubmed/31619230 http://dx.doi.org/10.1186/s12920-019-0581-9 |