Astragaloside IV regulates NF-κB-mediated cellular senescence and apoptosis of hepatic stellate cells to suppress PDGF-BB-induced activation

Activated hepatic stellate cells (HSCs) are the principal effectors during hepatic fibrosis, which is characterized by the accumulation of extracellular matrix. Therefore, present therapies and investigations into hepatic fibrosis mainly focus on the suppression of activated HSCs. Astragaloside IV (...

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Detalles Bibliográficos
Autores principales: Chen, Zhiwei, Yao, Ling, Liu, Yuanyuan, Pan, Zheng, Peng, Shuang, Wan, Guoguo, Cheng, Junxiong, Wang, Jianwei, Cao, Wenfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796432/
https://www.ncbi.nlm.nih.gov/pubmed/31641375
http://dx.doi.org/10.3892/etm.2019.8047

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