Cardiac troponin I autoantibody induces myocardial dysfunction by PTEN signaling activation

BACKGROUND: The objective of the current study was to study the molecular mechanism(s) underlying cardiac troponin I autoantibody (cTnIAAb) binding to cardiomyocyte and resultant myocardial damage/dysfunction. METHODS: cTnIAAb was purified from serum of 10 acute myocardial infarction (AMI) patients...

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Detalles Bibliográficos
Autores principales: Wu, Yu, Qin, Yang-hua, Liu, Yang, Zhu, Li, Zhao, Xian-xian, Liu, Yao-yang, Luo, Shi-wen, Tang, Gu-sheng, Shen, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796505/
https://www.ncbi.nlm.nih.gov/pubmed/31474552
http://dx.doi.org/10.1016/j.ebiom.2019.08.045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796505/
https://www.ncbi.nlm.nih.gov/pubmed/31474552
http://dx.doi.org/10.1016/j.ebiom.2019.08.045

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