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Direct transmission of within-host Mycobacterium tuberculosis diversity to secondary cases can lead to variable between-host heterogeneity without de novo mutation: A genomic investigation

BACKGROUND: Whole genome sequencing (WGS) has enabled the development of new approaches to track Mycobacterium tuberculosis (Mtb) transmission between tuberculosis (TB) cases but its utility may be challenged by the discovery that Mtb diversifies within hosts. Nevertheless, there is limited data on...

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Detalles Bibliográficos
Autores principales:	Séraphin, Marie Nancy, Norman, Anders, Rasmussen, Erik Michael, Gerace, Alexandra M., Chiribau, Calin B., Rowlinson, Marie-Claire, Lillebaek, Troels, Lauzardo, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796532/ https://www.ncbi.nlm.nih.gov/pubmed/31420303 http://dx.doi.org/10.1016/j.ebiom.2019.08.010

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