Utilizing the genomically adjusted radiation dose (GARD) to personalize adjuvant radiotherapy in triple negative breast cancer management

BACKGROUND: Utilizing the linear quadratic model and the radiosensitivity index (RSI), we have derived an expression for the genomically adjusted radiation dose (GARD) to model radiation dose effect. We hypothesize GARD is associated with local recurrence and can be used to optimize individual tripl...

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Detalles Bibliográficos
Autores principales: Ahmed, Kamran A., Liveringhouse, Casey L., Mills, Matthew N., Figura, Nicholas B., Grass, G. Daniel, Washington, Iman R., Harris, Eleanor E., Czerniecki, Brian J., Blumencranz, Peter W., Eschrich, Steven A., Scott, Jacob G., Diaz, Roberto, Torres-Roca, Javier F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796536/
https://www.ncbi.nlm.nih.gov/pubmed/31416721
http://dx.doi.org/10.1016/j.ebiom.2019.08.019

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