Augmenting the therapeutic efficacy of adenosine against pancreatic cancer by switching the Akt/p21-dependent senescence to apoptosis

BACKGROUND: There are many reports of the anti-tumour effects of exogenous adenosine in gastrointestinal tumours. Gemcitabine, a first line agent for patients with poor performance status, and adenosine have structural similarities. For these reasons, it is worth exploring the therapeutic efficacy o...

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Detalles Bibliográficos
Autores principales: Yang, Dongqin, Zhang, Qi, Ma, Yunfang, Che, Zhihui, Zhang, Wenli, Wu, Mengmeng, Wu, Lijun, Liu, Fuchen, Chu, Yiwei, Xu, Wei, McGrath, Mary, Song, Chunhua, Liu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796568/
https://www.ncbi.nlm.nih.gov/pubmed/31495718
http://dx.doi.org/10.1016/j.ebiom.2019.08.068

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