Inhibition of Nwd1 activity attenuates neuronal hyperexcitability and GluN2B phosphorylation in the hippocampus

BACKGROUND: NACHT and WD repeat domain-containing protein 1 (Nwd1) is a member of the innate immune protein subfamily. Nwd1 contributes to the androgen receptor signaling pathway and is involved in axonal growth. However, the mechanisms that underlie pathophysiological dysfunction in seizures remain...

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Detalles Bibliográficos
Autores principales: Yang, Qin, Huang, Zifeng, Luo, Yangfu, Zheng, Fangshuo, Hu, Yida, Liu, Hui, Zhu, Shuzhen, He, Miaoqing, Xu, Demei, Li, Yun, Yang, Min, Yang, Yi, Wei, Xiaobo, Gao, Xiaoya, Wang, Wei, Ma, Junhong, Ma, Yuanlin, Wang, Xuefeng, Wang, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796588/
https://www.ncbi.nlm.nih.gov/pubmed/31474551
http://dx.doi.org/10.1016/j.ebiom.2019.08.050

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