Calvarial Langerhans cell histiocytosis in an Adult: Typical imaging findings in an atypical age group

Langerhans Cell Histiocytosis (LCH) is a rare disorder characterized by neoplastic proliferation of Langerhans-type dendritic cells. LCH is most frequently encountered in the pediatric populations, and involvement of the skeletal system is a common manifestation. Herein, we report a case of LCH pres...

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Detalles Bibliográficos
Autores principales: Samara, Amjad, Nepute, Jordan, Lu, Hsiang-Chih, Perrin, Richard J., Eldaya, Rami W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Neuroradiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796621/
https://www.ncbi.nlm.nih.gov/pubmed/31641396
http://dx.doi.org/10.1016/j.radcr.2019.09.009
Descripción
Sumario:Langerhans Cell Histiocytosis (LCH) is a rare disorder characterized by neoplastic proliferation of Langerhans-type dendritic cells. LCH is most frequently encountered in the pediatric populations, and involvement of the skeletal system is a common manifestation. Herein, we report a case of LCH presented as an isolated skull lesion in a 66-year-old patient. This presentation has never been reported in the literature at this advanced age and suggests that, despite being exceptionally rare, clinicians should consider LCH in the differential diagnosis of skull lesions in the elderly with classical radiological appearance.

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