Similarities and differences in the biotransformation and transcriptomic responses of Caenorhabditis elegans and Haemonchus contortus to five different benzimidazole drugs

We have undertaken a detailed analysis of the biotransformation of five of the most therapeutically important benzimidazole anthelmintics - albendazole (ABZ), mebendazole (MBZ), thiabendazole (TBZ), oxfendazole (OxBZ) and fenbendazole (FBZ) - in Caenorhabditis elegans and the ruminant parasite Haemo...

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Detalles Bibliográficos
Autores principales: Stasiuk, S.J., MacNevin, G., Workentine, M.L., Gray, D., Redman, E., Bartley, D., Morrison, A., Sharma, N., Colwell, D., Ro, D.K., Gilleard, J.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796749/
https://www.ncbi.nlm.nih.gov/pubmed/31542693
http://dx.doi.org/10.1016/j.ijpddr.2019.09.001

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