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Obesity Mediates Apoptosis and Extracellular Matrix Metabolic Imbalances via MAPK Pathway Activation in Intervertebral Disk Degeneration

Obesity may promote intervertebral disc degeneration (IDD) by non-mechanical means, by influencing levels of free fatty acids which could impair cell metabolism. This study aims to establish metabolic factors in obesity-related IDD independent of mechanical loading. In clinical study, we retrospecti...

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Detalles Bibliográficos
Autores principales:	Zhang, Xuyang, Chen, Jian, Huang, Bao, Wang, Jiasheng, Shan, Zhi, Liu, Junhui, Chen, Yilei, Li, Shengyun, Fan, Shunwu, Zhao, Fengdong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796795/ https://www.ncbi.nlm.nih.gov/pubmed/31649558 http://dx.doi.org/10.3389/fphys.2019.01284

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