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Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate
Generation of widely differing and specialized cell types from a single totipotent zygote involves large-scale transcriptional changes and chromatin reorganization. Pioneer transcription factors play key roles in programming the epigenome and facilitating recruitment of additional regulatory factors...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796926/ https://www.ncbi.nlm.nih.gov/pubmed/31024170 http://dx.doi.org/10.1038/s41422-019-0168-1 |