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Optimizing Mannose “Click” Conjugation to Polymeric Nanoparticles for Targeted siRNA Delivery to Human and Murine Macrophages

[Image: see text] “Smart”, dual pH-responsive, and endosomolytic polymeric nanoparticles have demonstrated great potential for localized drug delivery, especially for siRNA delivery to the cytoplasm of cells. However, targeted delivery to a specific cell phenotype requires an additional level of fun...

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Detalles Bibliográficos
Autores principales:	Glass, Evan B., Masjedi, Shirin, Dudzinski, Stephanie O., Wilson, Andrew J., Duvall, Craig L., Yull, Fiona E., Giorgio, Todd D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2019
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796989/ https://www.ncbi.nlm.nih.gov/pubmed/31646220 http://dx.doi.org/10.1021/acsomega.9b01465

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