Large-scale, dynamin-like motions of the human guanylate binding protein 1 revealed by multi-resolution simulations

Guanylate binding proteins (GBPs) belong to the dynamin-related superfamily and exhibit various functions in the fight against infections. The functions of the human guanylate binding protein 1 (hGBP1) are tightly coupled to GTP hydrolysis and dimerization. Despite known crystal structures of the hG...

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Detalles Bibliográficos
Autores principales: Barz, Bogdan, Loschwitz, Jennifer, Strodel, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797221/
https://www.ncbi.nlm.nih.gov/pubmed/31589600
http://dx.doi.org/10.1371/journal.pcbi.1007193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797221/
https://www.ncbi.nlm.nih.gov/pubmed/31589600
http://dx.doi.org/10.1371/journal.pcbi.1007193

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