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Large-scale, dynamin-like motions of the human guanylate binding protein 1 revealed by multi-resolution simulations
Guanylate binding proteins (GBPs) belong to the dynamin-related superfamily and exhibit various functions in the fight against infections. The functions of the human guanylate binding protein 1 (hGBP1) are tightly coupled to GTP hydrolysis and dimerization. Despite known crystal structures of the hG...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797221/ https://www.ncbi.nlm.nih.gov/pubmed/31589600 http://dx.doi.org/10.1371/journal.pcbi.1007193 |