Loss of thymidine kinase 1 inhibits lung cancer growth and metastatic attributes by reducing GDF15 expression

Metabolic alterations that are critical for cancer cell growth and metastasis are one of the key hallmarks of cancer. Here, we show that thymidine kinase 1 (TK1) is significantly overexpressed in tumor samples from lung adenocarcinoma (LUAD) patients relative to normal controls, and this TK1 overexp...

Descripción completa

Detalles Bibliográficos
Autores principales: Malvi, Parmanand, Janostiak, Radoslav, Nagarajan, Arvindhan, Cai, Guoping, Wajapeyee, Narendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797230/
https://www.ncbi.nlm.nih.gov/pubmed/31589613
http://dx.doi.org/10.1371/journal.pgen.1008439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797230/
https://www.ncbi.nlm.nih.gov/pubmed/31589613
http://dx.doi.org/10.1371/journal.pgen.1008439

Ejemplares similares