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Experimental characterization of two archaeal inosine 5'-monophosphate cyclohydrolases

There is variability as to how archaea catalyze the final step of de novo purine biosynthesis to form inosine 5’-monophosphate (IMP) from 5-formamidoimidazole-4-carboxamide ribonucleotide (FAICAR). Although non-archaea almost uniformly use the bifunctional PurH protein, which has an N-terminal IMP c...

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Detalles Bibliográficos
Autores principales:	Hunter, Caroline A., Plymale, Nicholas I., Smee, Kevin M., Sarisky, Catherine A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797443/ https://www.ncbi.nlm.nih.gov/pubmed/31622427 http://dx.doi.org/10.1371/journal.pone.0223983

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