Control of RNA viruses in mosquito cells through the acquisition of vDNA and endogenous viral elements

Aedes aegypti transmit pathogenic arboviruses while the mosquito itself tolerates the infection. We examine a piRNA-based immunity that relies on the acquisition of viral derived cDNA (vDNA) and how this pathway discriminates between self and non-self. The piRNAs derived from these vDNAs are essenti...

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Detalles Bibliográficos
Autores principales: Tassetto, Michel, Kunitomi, Mark, Whitfield, Zachary J, Dolan, Patrick T, Sánchez-Vargas, Irma, Garcia-Knight, Miguel, Ribiero, Isabel, Chen, Taotao, Olson, Ken E, Andino, Raul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797480/
https://www.ncbi.nlm.nih.gov/pubmed/31621580
http://dx.doi.org/10.7554/eLife.41244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797480/
https://www.ncbi.nlm.nih.gov/pubmed/31621580
http://dx.doi.org/10.7554/eLife.41244

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