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Control of RNA viruses in mosquito cells through the acquisition of vDNA and endogenous viral elements
Aedes aegypti transmit pathogenic arboviruses while the mosquito itself tolerates the infection. We examine a piRNA-based immunity that relies on the acquisition of viral derived cDNA (vDNA) and how this pathway discriminates between self and non-self. The piRNAs derived from these vDNAs are essenti...
Autores principales: | Tassetto, Michel, Kunitomi, Mark, Whitfield, Zachary J, Dolan, Patrick T, Sánchez-Vargas, Irma, Garcia-Knight, Miguel, Ribiero, Isabel, Chen, Taotao, Olson, Ken E, Andino, Raul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797480/ https://www.ncbi.nlm.nih.gov/pubmed/31621580 http://dx.doi.org/10.7554/eLife.41244 |
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