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Aurora B prevents aneuploidy via MAD2 during the first mitotic cleavage in oxidatively damaged embryos

OBJECTIVES: A high rate of chromosome aneuploidy is exhibited in in vitro fertilization (IVF)‐derived embryos. Our previous experiments suggested that reactive oxygen species (ROS) can activate Mad2, a key protein in the spindle assembly checkpoint (SAC), and delay the first mitotic, providing time...

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Detalles Bibliográficos
Autores principales:	Li, Jiena, Ha, Siyao, Li, Zhiling, Huang, Yue, Lin, En, Xiao, Wanfen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797512/ https://www.ncbi.nlm.nih.gov/pubmed/31264311 http://dx.doi.org/10.1111/cpr.12657

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