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CRM197 reverses paclitaxel resistance by inhibiting the NAC‐1/Gadd45 pathway in paclitaxel‐resistant ovarian cancer cells
Heparin‐binding epidermal growth factor‐like growth factor (HB‐EGF) is a new promising target for the treatment of ovarian cancer. Our previous study showed that cross‐reacting material 197 (CRM197), a specific HB‐EGF inhibitor, significantly reverses resistance against paclitaxel in paclitaxel‐resi...
Autores principales: | Tang, Xiao‐han, Li, Hui, Zheng, Xiu‐shuang, Lu, Mei‐song, An, Yuan, Zhang, Xiao‐lei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797568/ https://www.ncbi.nlm.nih.gov/pubmed/31490008 http://dx.doi.org/10.1002/cam4.2512 |
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