Multi-targeted kinase inhibition alleviates mTOR inhibitor resistance in triple-negative breast cancer

PURPOSE: Owing to its genetic heterogeneity and acquired resistance, triple-negative breast cancer (TNBC) is not responsive to single-targeted therapy, causing disproportional cancer-related death worldwide. Combined targeted therapy strategies to block interactive oncogenic signaling networks are b...

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Detalles Bibliográficos
Autores principales: He, Jichao, McLaughlin, Ronan P., van der Noord, Vera, Foekens, John A., Martens, John W. M., van Westen, Gerard, Zhang, Yinghui, van de Water, Bob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Preclinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797661/
https://www.ncbi.nlm.nih.gov/pubmed/31388935
http://dx.doi.org/10.1007/s10549-019-05380-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797661/
https://www.ncbi.nlm.nih.gov/pubmed/31388935
http://dx.doi.org/10.1007/s10549-019-05380-z

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