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Cytosolic 10-formyltetrahydrofolate dehydrogenase regulates glycine metabolism in mouse liver

ALDH1L1 (10-formyltetrahydrofolate dehydrogenase), an enzyme of folate metabolism highly expressed in liver, metabolizes 10-formyltetrahydrofolate to produce tetrahydrofolate (THF). This reaction might have a regulatory function towards reduced folate pools, de novo purine biosynthesis, and the flux...

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Detalles Bibliográficos
Autores principales:	Krupenko, Natalia I., Sharma, Jaspreet, Pediaditakis, Peter, Fekry, Baharan, Helke, Kristi L., Du, Xiuxia, Sumner, Susan, Krupenko, Sergey A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797707/ https://www.ncbi.nlm.nih.gov/pubmed/31624291 http://dx.doi.org/10.1038/s41598-019-51397-1

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