Identification and Validation of a Novel Biologics Target in Triple Negative Breast Cancer

The goal of this study was to identify a novel target for antibody-drug conjugate (ADC) development in triple negative breast cancer (TNBC), which has limited treatment options, using gene expression datasets and in vitro siRNA/CRISPR and in vivo functional assays. We analyzed 4467 breast cancers an...

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Detalles Bibliográficos
Autores principales: Wali, Vikram B., Patwardhan, Gauri A., Pelekanou, Vasiliki, Karn, Thomas, Cao, Jian, Ocana, Alberto, Yan, Qin, Nelson, Bryce, Hatzis, Christos, Pusztai, Lajos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797726/
https://www.ncbi.nlm.nih.gov/pubmed/31624295
http://dx.doi.org/10.1038/s41598-019-51453-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797726/
https://www.ncbi.nlm.nih.gov/pubmed/31624295
http://dx.doi.org/10.1038/s41598-019-51453-w

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