Transforming protein-polymer conjugate purification by tuning protein solubility

Almost all commercial proteins are purified using ammonium sulfate precipitation. Protein-polymer conjugates are synthesized from pure starting materials, and the struggle to separate conjugates from polymer, native protein, and from isomers has vexed scientists for decades. We have discovered that...

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Detalles Bibliográficos
Autores principales: Baker, Stefanie L., Munasinghe, Aravinda, Kaupbayeva, Bibifatima, Rebecca Kang, Nin, Certiat, Marie, Murata, Hironobu, Matyjaszewski, Krzysztof, Lin, Ping, Colina, Coray M., Russell, Alan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797786/
https://www.ncbi.nlm.nih.gov/pubmed/31624254
http://dx.doi.org/10.1038/s41467-019-12612-9

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