Histone H3K23-specific acetylation by MORF is coupled to H3K14 acylation

Acetylation of histone H3K23 has emerged as an essential posttranslational modification associated with cancer and learning and memory impairment, yet our understanding of this epigenetic mark remains insufficient. Here, we identify the native MORF complex as a histone H3K23-specific acetyltransfera...

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Detalles Bibliográficos
Autores principales: Klein, Brianna J., Jang, Suk Min, Lachance, Catherine, Mi, Wenyi, Lyu, Jie, Sakuraba, Shun, Krajewski, Krzysztof, Wang, Wesley W., Sidoli, Simone, Liu, Jiuyang, Zhang, Yi, Wang, Xiaolu, Warfield, Becka M., Kueh, Andrew J., Voss, Anne K., Thomas, Tim, Garcia, Benjamin A., Liu, Wenshe R., Strahl, Brian D., Kono, Hidetoshi, Li, Wei, Shi, Xiaobing, Côté, Jacques, Kutateladze, Tatiana G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797804/
https://www.ncbi.nlm.nih.gov/pubmed/31624313
http://dx.doi.org/10.1038/s41467-019-12551-5

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