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KRAS and BRAF mutations induce anoikis resistance and characteristic 3D phenotypes in Caco-2 cells
In a number of types of cancer, anoikis, a form of apoptosis induced by loss of extracellular matrix (ECM) attachment, is disturbed. Anoikis resistance is essential in the formation of metastases. A recent study identified carcinoma cell subpopulations surviving without ECM contact in pathological s...
Autores principales: | Patankar, Madhura, Eskelinen, Sinikka, Tuomisto, Anne, Mäkinen, Markus J., Karttunen, Tuomo J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797985/ https://www.ncbi.nlm.nih.gov/pubmed/31545494 http://dx.doi.org/10.3892/mmr.2019.10693 |
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