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An Integrated Pipeline for Combining in vitro Data and Mathematical Models Using a Bayesian Parameter Inference Approach to Characterize Spatio-temporal Chemokine Gradient Formation
All protective and pathogenic immune and inflammatory responses rely heavily on leukocyte migration and localization. Chemokines are secreted chemoattractants that orchestrate the positioning and migration of leukocytes through concentration gradients. The mechanisms underlying chemokine gradient es...
Autores principales: | Kalogiros, Dimitris I., Russell, Matthew J., Bonneuil, Willy V., Frattolin, Jennifer, Watson, Daniel, Moore, James E., Kypraios, Theodore, Brook, Bindi S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798077/ https://www.ncbi.nlm.nih.gov/pubmed/31681255 http://dx.doi.org/10.3389/fimmu.2019.01986 |
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