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Osteochondral Autologous Transplantation for Treating Patellar High-Grade Chondral Defects: A Systematic Review

BACKGROUND: Patellar cartilage defects account for 34.6% of defects found during routine arthroscopy. These defects pose a challenge in orthopaedic surgery because they have been associated with worse outcomes after surgical repair compared with other chondral lesions within the knee. PURPOSE: To sy...

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Autores principales: Donoso, Rodrigo, Figueroa, David, Espinoza, Jaime, Yañez, Claudio, Saavedra, Jamil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798165/
https://www.ncbi.nlm.nih.gov/pubmed/31667196
http://dx.doi.org/10.1177/2325967119876618
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author Donoso, Rodrigo
Figueroa, David
Espinoza, Jaime
Yañez, Claudio
Saavedra, Jamil
author_facet Donoso, Rodrigo
Figueroa, David
Espinoza, Jaime
Yañez, Claudio
Saavedra, Jamil
author_sort Donoso, Rodrigo
collection PubMed
description BACKGROUND: Patellar cartilage defects account for 34.6% of defects found during routine arthroscopy. These defects pose a challenge in orthopaedic surgery because they have been associated with worse outcomes after surgical repair compared with other chondral lesions within the knee. PURPOSE: To systematically review the literature for evidence on results of osteochondral autologous transplantation (OAT) for the management of isolated patellar cartilage high-grade defects (International Cartilage Repair Society [ICRS] grade 3-4). STUDY DESIGN: Systematic review; Level of evidence, 4. METHODS: A systematic review of the literature was performed to find studies that addressed outcomes regarding OAT to treat patellar high-grade cartilage defects (ICRS grade 3-4). Studies addressing patient-reported outcomes, return to sports, or magnetic resonance imaging (MRI) at follow-up after isolated OAT procedures for patellar cartilage defects were included. RESULTS: A total of 5 studies were included in this review. We were not able to perform a meta-analysis as no studies had available data. A total of 102 patients who received an isolated OAT for a patellar chondral defect were included in these 5 studies. All patients showed significant improvement at final follow-up based on the following patient-reported outcome scores: Lysholm, International Knee Documentation Committee, Kujala, Tegner, and 36-Item Short Form Health Survey. We found that 4 studies used MRI during the first postoperative year to assess osteochondral plug integration and positioning. The results demonstrated that most plugs were integrated and correctly positioned when evaluated at follow-up, conducted on average after 12 months. Whether patients were able to return to sports was queried in 2 of the included studies, revealing that patients could return to their previous level in most cases (Tegner score, 5-9 at 2 years after surgery). CONCLUSION: Results indicate that OAT is a safe and reliable technique to treat patellar high-grade osteochondral defects, allowing for significant improvement in patient-reported outcomes and return to sports.
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spelling pubmed-67981652019-10-30 Osteochondral Autologous Transplantation for Treating Patellar High-Grade Chondral Defects: A Systematic Review Donoso, Rodrigo Figueroa, David Espinoza, Jaime Yañez, Claudio Saavedra, Jamil Orthop J Sports Med Article BACKGROUND: Patellar cartilage defects account for 34.6% of defects found during routine arthroscopy. These defects pose a challenge in orthopaedic surgery because they have been associated with worse outcomes after surgical repair compared with other chondral lesions within the knee. PURPOSE: To systematically review the literature for evidence on results of osteochondral autologous transplantation (OAT) for the management of isolated patellar cartilage high-grade defects (International Cartilage Repair Society [ICRS] grade 3-4). STUDY DESIGN: Systematic review; Level of evidence, 4. METHODS: A systematic review of the literature was performed to find studies that addressed outcomes regarding OAT to treat patellar high-grade cartilage defects (ICRS grade 3-4). Studies addressing patient-reported outcomes, return to sports, or magnetic resonance imaging (MRI) at follow-up after isolated OAT procedures for patellar cartilage defects were included. RESULTS: A total of 5 studies were included in this review. We were not able to perform a meta-analysis as no studies had available data. A total of 102 patients who received an isolated OAT for a patellar chondral defect were included in these 5 studies. All patients showed significant improvement at final follow-up based on the following patient-reported outcome scores: Lysholm, International Knee Documentation Committee, Kujala, Tegner, and 36-Item Short Form Health Survey. We found that 4 studies used MRI during the first postoperative year to assess osteochondral plug integration and positioning. The results demonstrated that most plugs were integrated and correctly positioned when evaluated at follow-up, conducted on average after 12 months. Whether patients were able to return to sports was queried in 2 of the included studies, revealing that patients could return to their previous level in most cases (Tegner score, 5-9 at 2 years after surgery). CONCLUSION: Results indicate that OAT is a safe and reliable technique to treat patellar high-grade osteochondral defects, allowing for significant improvement in patient-reported outcomes and return to sports. SAGE Publications 2019-10-17 /pmc/articles/PMC6798165/ /pubmed/31667196 http://dx.doi.org/10.1177/2325967119876618 Text en © The Author(s) 2019 http://creativecommons.org/licenses/by-nc-nd/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 License (http://www.creativecommons.org/licenses/by-nc-nd/4.0/) which permits non-commercial use, reproduction and distribution of the work as published without adaptation or alteration, without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Article
Donoso, Rodrigo
Figueroa, David
Espinoza, Jaime
Yañez, Claudio
Saavedra, Jamil
Osteochondral Autologous Transplantation for Treating Patellar High-Grade Chondral Defects: A Systematic Review
title Osteochondral Autologous Transplantation for Treating Patellar High-Grade Chondral Defects: A Systematic Review
title_full Osteochondral Autologous Transplantation for Treating Patellar High-Grade Chondral Defects: A Systematic Review
title_fullStr Osteochondral Autologous Transplantation for Treating Patellar High-Grade Chondral Defects: A Systematic Review
title_full_unstemmed Osteochondral Autologous Transplantation for Treating Patellar High-Grade Chondral Defects: A Systematic Review
title_short Osteochondral Autologous Transplantation for Treating Patellar High-Grade Chondral Defects: A Systematic Review
title_sort osteochondral autologous transplantation for treating patellar high-grade chondral defects: a systematic review
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798165/
https://www.ncbi.nlm.nih.gov/pubmed/31667196
http://dx.doi.org/10.1177/2325967119876618
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