Ribavirin for Chronic Hepatitis E Virus Infection in Ibrutinib-Exposed Patients

Ibrutinib is an oral first-in-class Bruton’s tyrosine kinase inhibitor approved for the therapy of various B-cell lymphoid malignancies. Among ibrutinib-related infections, viral hepatitis are poorly described. We report our single-center experience with 4 cases of chronic hepatitis E virus infectio...

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Detalles Bibliográficos
Autores principales: Protin, Caroline, Abravanel, Florence, Alric, Laurent, Tavitian, Suzanne, Obéric, Lucie, Izopet, Jacques, Martin-Blondel, Guillaume, Ysebaert, Loic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798245/
https://www.ncbi.nlm.nih.gov/pubmed/31660412
http://dx.doi.org/10.1093/ofid/ofz345
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author Protin, Caroline
Abravanel, Florence
Alric, Laurent
Tavitian, Suzanne
Obéric, Lucie
Izopet, Jacques
Martin-Blondel, Guillaume
Ysebaert, Loic
author_facet Protin, Caroline
Abravanel, Florence
Alric, Laurent
Tavitian, Suzanne
Obéric, Lucie
Izopet, Jacques
Martin-Blondel, Guillaume
Ysebaert, Loic
author_sort Protin, Caroline
collection PubMed
description Ibrutinib is an oral first-in-class Bruton’s tyrosine kinase inhibitor approved for the therapy of various B-cell lymphoid malignancies. Among ibrutinib-related infections, viral hepatitis are poorly described. We report our single-center experience with 4 cases of chronic hepatitis E virus infection and their management with ribavirin.
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spelling pubmed-67982452019-10-28 Ribavirin for Chronic Hepatitis E Virus Infection in Ibrutinib-Exposed Patients Protin, Caroline Abravanel, Florence Alric, Laurent Tavitian, Suzanne Obéric, Lucie Izopet, Jacques Martin-Blondel, Guillaume Ysebaert, Loic Open Forum Infect Dis Brief Report Ibrutinib is an oral first-in-class Bruton’s tyrosine kinase inhibitor approved for the therapy of various B-cell lymphoid malignancies. Among ibrutinib-related infections, viral hepatitis are poorly described. We report our single-center experience with 4 cases of chronic hepatitis E virus infection and their management with ribavirin. Oxford University Press 2019-07-28 /pmc/articles/PMC6798245/ /pubmed/31660412 http://dx.doi.org/10.1093/ofid/ofz345 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Protin, Caroline
Abravanel, Florence
Alric, Laurent
Tavitian, Suzanne
Obéric, Lucie
Izopet, Jacques
Martin-Blondel, Guillaume
Ysebaert, Loic
Ribavirin for Chronic Hepatitis E Virus Infection in Ibrutinib-Exposed Patients
title Ribavirin for Chronic Hepatitis E Virus Infection in Ibrutinib-Exposed Patients
title_full Ribavirin for Chronic Hepatitis E Virus Infection in Ibrutinib-Exposed Patients
title_fullStr Ribavirin for Chronic Hepatitis E Virus Infection in Ibrutinib-Exposed Patients
title_full_unstemmed Ribavirin for Chronic Hepatitis E Virus Infection in Ibrutinib-Exposed Patients
title_short Ribavirin for Chronic Hepatitis E Virus Infection in Ibrutinib-Exposed Patients
title_sort ribavirin for chronic hepatitis e virus infection in ibrutinib-exposed patients
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798245/
https://www.ncbi.nlm.nih.gov/pubmed/31660412
http://dx.doi.org/10.1093/ofid/ofz345
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