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Iron Accumulates in Retinal Vascular Endothelial Cells But Has Minimal Retinal Penetration After IP Iron Dextran Injection in Mice

PURPOSE: Iron supplementation therapy is used for iron-deficiency anemia but has been associated with macular degeneration in a 43-year-old patient. Iron entry into the neurosensory retina (NSR) can be toxic. It is important to determine conditions under which serum iron might cross the blood retina...

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Detalles Bibliográficos
Autores principales: Shu, Wanting, Baumann, Bailey H., Song, Ying, Liu, Yingrui, Wu, Xingwei, Dunaief, Joshua L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798310/
https://www.ncbi.nlm.nih.gov/pubmed/31634395
http://dx.doi.org/10.1167/iovs.19-28250