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Clinical insights gained by refining the 2016 WHO classification of diffuse gliomas with: EGFR amplification, TERT mutations, PTEN deletion and MGMT methylation

BACKGROUND: Significant advances in the molecular profiling of gliomas, led the 2016 World Health Organization (WHO) Classification to include, for the first-time, molecular biomarkers in glioma diagnosis: IDH mutations and 1p/19q codeletion. Here, we evaluated the effect of this new classification...

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Detalles Bibliográficos
Autores principales:	Brito, Cheila, Azevedo, Ana, Esteves, Susana, Marques, Ana Rita, Martins, Carmo, Costa, Ilda, Mafra, Manuela, Bravo Marques, José M., Roque, Lúcia, Pojo, Marta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798410/ https://www.ncbi.nlm.nih.gov/pubmed/31623593 http://dx.doi.org/10.1186/s12885-019-6177-0

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