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DeepImpute: an accurate, fast, and scalable deep neural network method to impute single-cell RNA-seq data
Single-cell RNA sequencing (scRNA-seq) offers new opportunities to study gene expression of tens of thousands of single cells simultaneously. We present DeepImpute, a deep neural network-based imputation algorithm that uses dropout layers and loss functions to learn patterns in the data, allowing fo...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798445/ https://www.ncbi.nlm.nih.gov/pubmed/31627739 http://dx.doi.org/10.1186/s13059-019-1837-6 |