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circRNA circAF4 functions as an oncogene to regulate MLL-AF4 fusion protein expression and inhibit MLL leukemia progression

BACKGROUND: Circular RNAs (circRNAs) represent a type of endogenous noncoding RNAs that are generated by back-splicing events and favor repetitive sequences. Recent studies have reported that cancer-associated chromosomal translocations could juxtapose distant complementary repetitive intronic seque...

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Detalles Bibliográficos
Autores principales: Huang, Wei, Fang, Ke, Chen, Tian-Qi, Zeng, Zhan-Cheng, Sun, Yu-Meng, Han, Cai, Sun, Lin-Yu, Chen, Zhen-Hua, Yang, Qian-Qian, Pan, Qi, Luo, Xue-Qun, Wang, Wen-Tao, Chen, Yue-Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798510/
https://www.ncbi.nlm.nih.gov/pubmed/31623653
http://dx.doi.org/10.1186/s13045-019-0800-z

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