3533 Delayed Administration Of Angiotensin Receptor (AT2R) Agonist C21 Downregulates Diabetes Induced Pro-Inflammatory Microglia Activation To Improve Cognitive & Functional Recovery Post Stroke: Therapeutic Indications For The Treatment Of Vascular Cognitive

OBJECTIVES/SPECIFIC AIMS: The study aim was to 1) elucidate mechanisms contributing to the evolution of PSCI using a clinically relevant model of diabetes, a major risk factor for stroke and cognitive impairment, and 2) develop angiotensin type 2 receptor (AT2R) agonism as a therapeutic target. METH...

Descripción completa

Detalles Bibliográficos
Autores principales: Jackson, Ladonya, Dong, Guangkuo, Fagan, Susan, Ergul, Adviye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2019
Materias:
Basic/Translational Science/Team Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798528/
http://dx.doi.org/10.1017/cts.2019.21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798528/
http://dx.doi.org/10.1017/cts.2019.21

Ejemplares similares