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3533 Delayed Administration Of Angiotensin Receptor (AT2R) Agonist C21 Downregulates Diabetes Induced Pro-Inflammatory Microglia Activation To Improve Cognitive & Functional Recovery Post Stroke: Therapeutic Indications For The Treatment Of Vascular Cognitive
OBJECTIVES/SPECIFIC AIMS: The study aim was to 1) elucidate mechanisms contributing to the evolution of PSCI using a clinically relevant model of diabetes, a major risk factor for stroke and cognitive impairment, and 2) develop angiotensin type 2 receptor (AT2R) agonism as a therapeutic target. METH...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cambridge University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798528/ http://dx.doi.org/10.1017/cts.2019.21 |