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2543 High concentrations of CXCL12 decrease pancreatic adenocarcinoma growth

OBJECTIVES/SPECIFIC AIMS: We hypothesized that CXCL12, as a biased dimer variant or secreted at dimer-dominant concentrations, would influence PDAC growth and progression. METHODS/STUDY POPULATION: PDAC cells were genetically manipulated to express dimer-promoting levels of CXCL12. These cells were...

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Detalles Bibliográficos
Autores principales:	Vonderhaar, Emily, Dwinell, Michael, Roy, Ishan R., McAllister, Donna M., Dwinell, Michael B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cambridge University Press 2018
Materias:	Basic/Translational Science/Team Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798694/ http://dx.doi.org/10.1017/cts.2018.79

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