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3343 Identification of host-microbial interaction networks that mediate intestinal epithelial barrier function in necrotizing enterocolitis

OBJECTIVES/SPECIFIC AIMS: The central goal of this proposal is to characterize the mechanisms that mediate success or failure of immature intestinal barrier in necrotizing enterocilitis. METHODS/STUDY POPULATION: To do this, I will utilize stem cell derived human intestinal organoids (HIOs), an inno...

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Detalles Bibliográficos
Autores principales:	Hill, David R, Cieza, Roberto, Yadagiri, Veda K., Tarr, Phillip, Spence, Jason R., Young, Vincent B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cambridge University Press 2019
Materias:	Basic/Translational Science/Team Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798771/ http://dx.doi.org/10.1017/cts.2019.34

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