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3448 Macrophages, APOL1 Genotype, & Immunometabolism in CVD (MAGIC

OBJECTIVES/SPECIFIC AIMS: This study aims to understand the potential immunomudualtory effect of APOL1 variants in auto-antigen activated myeloid cells by assessing lysosomal integrity in activated cells expressing APOL1. The primary stimuli were: 1. ssRNA hY3 as a proxy for the Ro immune complex; 2...

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Detalles Bibliográficos
Autores principales: Blazer, Ashira D., Chang, Miao, Robins, Kimberly, Buyon, Jill, Clancy, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798889/
http://dx.doi.org/10.1017/cts.2019.339

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