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3506 PRMT5 is a novel therapeutic target to enhance radiation therapy for cancer treatment

OBJECTIVES/SPECIFIC AIMS: Prostate cancer is the second leading cause of cancer-related death among men in the U.S. and over half of all prostate cancer patients receive radiation therapy (RT). RT induces double-strand breaks (DSBs) in DNA which are lethal to cells if not repaired. While potentially...

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Detalles Bibliográficos
Autores principales: Owens, Jake L, Beketova, Elena, Tinsley, Samantha, Asberry, Andrew, Deng, Xuehong, Hu, Chang-Deng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798890/
http://dx.doi.org/10.1017/cts.2019.257