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2472: Subjective cognitive complaints in mild traumatic brain injury and 6-month return to work prediction: A TRACK-TBI Study

OBJECTIVES/SPECIFIC AIMS: About 75% of the estimated 2.5 million traumatic brain injuries (TBIs) diagnosed annually classify as mild TBI (mTBI); yet cognitive impairments associated with poor patient outcomes can persist for weeks to years. mTBI symptoms are difficult to measure objectively and ofte...

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Autores principales: Phillips, Debra, Ngwenya, Laura, Huang, Michael, Saeng Hong, Oi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798914/
http://dx.doi.org/10.1017/cts.2017.112
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author Phillips, Debra
Ngwenya, Laura
Huang, Michael
Saeng Hong, Oi
author_facet Phillips, Debra
Ngwenya, Laura
Huang, Michael
Saeng Hong, Oi
author_sort Phillips, Debra
collection PubMed
description OBJECTIVES/SPECIFIC AIMS: About 75% of the estimated 2.5 million traumatic brain injuries (TBIs) diagnosed annually classify as mild TBI (mTBI); yet cognitive impairments associated with poor patient outcomes can persist for weeks to years. mTBI symptoms are difficult to measure objectively and often remain undiagnosed in the context of an unknown cognitive baseline. Formal neuropsychological exams hold limited utility due to their extensive resource burden. We aimed to define the clinical importance of a 4-question assessment of subjective cognitive complaints (SCC) in predicting return to work at 6 months following mTBI. METHODS/STUDY POPULATION: mTBI participants from the prospective Transforming Research and Clinical Knowledge in Traumatic Brain Injury Pilot Study were included. A self-report affirmation to at least 1 of 4 subjective cognitive symptoms yielded positive SCC. Regression analysis was used to determine factors associated with return to work by 6-months. RESULTS/ANTICIPATED RESULTS: Of 479 enrolled participants with mTBI, 271 (57%) had complete follow-up data. Of which, 156 (58%) had at least sheltered employment at enrollment. Thirty-four (22%) of workers had no return to work at 6-months. Demographics, prior education, presenting injury severity, work status, and post-traumatic stress disorder were associated with return to work. SCC was associated with lower odds of return to work by 6-months (OR=0.11, p=0.01). DISCUSSION/SIGNIFICANCE OF IMPACT: We suggest a concise 4-question assessment of SCC may be clinically relevant in estimating the likelihood of return to work by 6 months post-mTBI.
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spelling pubmed-67989142019-10-28 2472: Subjective cognitive complaints in mild traumatic brain injury and 6-month return to work prediction: A TRACK-TBI Study Phillips, Debra Ngwenya, Laura Huang, Michael Saeng Hong, Oi J Clin Transl Sci Clinical Epidemiology OBJECTIVES/SPECIFIC AIMS: About 75% of the estimated 2.5 million traumatic brain injuries (TBIs) diagnosed annually classify as mild TBI (mTBI); yet cognitive impairments associated with poor patient outcomes can persist for weeks to years. mTBI symptoms are difficult to measure objectively and often remain undiagnosed in the context of an unknown cognitive baseline. Formal neuropsychological exams hold limited utility due to their extensive resource burden. We aimed to define the clinical importance of a 4-question assessment of subjective cognitive complaints (SCC) in predicting return to work at 6 months following mTBI. METHODS/STUDY POPULATION: mTBI participants from the prospective Transforming Research and Clinical Knowledge in Traumatic Brain Injury Pilot Study were included. A self-report affirmation to at least 1 of 4 subjective cognitive symptoms yielded positive SCC. Regression analysis was used to determine factors associated with return to work by 6-months. RESULTS/ANTICIPATED RESULTS: Of 479 enrolled participants with mTBI, 271 (57%) had complete follow-up data. Of which, 156 (58%) had at least sheltered employment at enrollment. Thirty-four (22%) of workers had no return to work at 6-months. Demographics, prior education, presenting injury severity, work status, and post-traumatic stress disorder were associated with return to work. SCC was associated with lower odds of return to work by 6-months (OR=0.11, p=0.01). DISCUSSION/SIGNIFICANCE OF IMPACT: We suggest a concise 4-question assessment of SCC may be clinically relevant in estimating the likelihood of return to work by 6 months post-mTBI. Cambridge University Press 2018-05-10 /pmc/articles/PMC6798914/ http://dx.doi.org/10.1017/cts.2017.112 Text en © The Association for Clinical and Translational Science 2018 http://creativecommons.org/licenses/by/4.0/ This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Epidemiology
Phillips, Debra
Ngwenya, Laura
Huang, Michael
Saeng Hong, Oi
2472: Subjective cognitive complaints in mild traumatic brain injury and 6-month return to work prediction: A TRACK-TBI Study
title 2472: Subjective cognitive complaints in mild traumatic brain injury and 6-month return to work prediction: A TRACK-TBI Study
title_full 2472: Subjective cognitive complaints in mild traumatic brain injury and 6-month return to work prediction: A TRACK-TBI Study
title_fullStr 2472: Subjective cognitive complaints in mild traumatic brain injury and 6-month return to work prediction: A TRACK-TBI Study
title_full_unstemmed 2472: Subjective cognitive complaints in mild traumatic brain injury and 6-month return to work prediction: A TRACK-TBI Study
title_short 2472: Subjective cognitive complaints in mild traumatic brain injury and 6-month return to work prediction: A TRACK-TBI Study
title_sort 2472: subjective cognitive complaints in mild traumatic brain injury and 6-month return to work prediction: a track-tbi study
topic Clinical Epidemiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798914/
http://dx.doi.org/10.1017/cts.2017.112
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