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2081: Phenotypic characterization of the CD4+ T-cell response during anti-CTLA4 therapy with ipilimumab in melanoma patients

OBJECTIVES/SPECIFIC AIMS: To characterize the CD4+ T-cell response during CTLA-4 blockade immunotherapy with ipilimumab in patients with metastatic melanoma by correlating cytokine profiles with phenotypic changes in the intratumoral lymphocyte compartment of tumor biopsies obtained before and after...

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Detalles Bibliográficos
Autores principales:	Sherani, Farha, Moogk, Duane, Bapodra, Anuj, Malecek, Karolina, Moran, Una, Lee, Yesung, Osman, Iman, Krogsgaard, Michelle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cambridge University Press 2018
Materias:	Mechanistic Basic to Clinical
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6799028/ http://dx.doi.org/10.1017/cts.2017.199

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