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2290: Control of atherosclerosis regression by LXRα S198 phosphorylation
OBJECTIVES/SPECIFIC AIMS: Accumulation of cholesterol-laden macrophages in arterial walls leads to atherosclerosis. LXRs induce expression of genes that are atheroprotective in macrophages including CCR7, a chemokine receptor that promotes their emigration from the plaque. CCR7 expression has been s...
Autores principales: | Shrestha, Elina, Voisin, Maud, Barrett, Tessa J., Nishi, Hitoo, Pineda-Torra, Inés, Fisher, Edward A., Garabedian, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6799160/ http://dx.doi.org/10.1017/cts.2017.34 |
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